PENGARUH WAKTU PENYIMPANAN SAMPEL SERUM TERHADAP NILAI CRP (C-REACTIVE PROTEIN) PADA SUSPECT TUBERCULOSIS

CRP (C-Reactive Protein) is a protein found in the blood produced by the liver that will increase in response to infection, injury or inflammation. Tuberculosis (TB) is a direct infectious disease caused by the TB bacteria Mycobacterium Tuberculosis. Supporting studies to confirm the diagnosis of pulmonary tuberculosis include immunoserology. By looking at the results of the examination of the amount of C-reactive protein CRP value is determined based on clinical tests with the agglutination test method , and the analysis results are obtained in semi-quantitative form. The agglutination test is based on the immune reaction between CRP from the subject's serum and anti-CRP bound to latex particles. Serum storage needs to be considered because if serum sampling and the place where the sample is examined are not in close proximity or in one place, the serum place must be stored with refrigeration. It is important in maintaining the quality of the examination material to read the examination results. This study was conducted to determine the effect of delaying samples for 7 days and 8 days at 4℃ with immediate samples on CRP levels. The data were analyzed by man whitney test to see the difference between each treatment, the results showed that the hypothesis was rejected because the asymp.sig (2-tailed) value was 1.000>0.05, so it can be concluded that there is no significant effect on CRP values for sample storage time for 7 hearts and 8 days at 4℃.

Keywords: CRP, Tuberculosis, Serum delay