ANALISIS KADAR KREATININ DENGAN SAMPEL SERUM DAN PLASMA HEPARIN PADA PASIEN GAGAL GINJAL KRONIK

One of the laboratory tests carried out to determine kidney function is creatinine. Creatinine is a product of endogenous metabolism from skeletal muscle which is excreted in the urine through glomerular filtration. High and low levels of creatinine in the blood are used as an important indicator in determining kidney function disorders. Creatinine is excreted by the kidneys through a combination of filtration and secretion, its concentration is relatively constant in plasma from day to day, levels greater than normal values indicate impaired kidney function. To determine the significant difference in the results of creatinine levels with serum and plasma heparin samples in patients with chronic renal failure, research was carried out using a cross sectional approach. Analytical research methods and subjects studied were 20 samples. The respective samples were treated as heparinized serum and plasma and then checked for creatinine levels. Statistical data analysis used the Independent sample T test. The average value of creatinine levels in serum was 8.29 mg/dL and the average value of creatinine levels in heparin plasma samples was 8.21 md/dL. And the results of statistical tests using the independent sample T test obtained a sig value of 0.984 (p-value ≥ 0.05) This shows that H0 is accepted or there is no difference in the average creatinine levels in Heparin serum and plasma samples

Key words: creatinine levels, serum, plasma heparin